News Summary

• Artificial intelligence (AI)-enhanced electrocardiogram (ECG) analysis offers a scalable approach to the early detection of cardiovascular disease.
• Structural heart disease (SHD), a broad category encompassing conditions that affect the valves, walls and chambers of the heart, is a major contributor to cardiovascular morbidity and mortality.
• Here we present a sentinel case in which AI-enabled ECG analysis facilitated the detection of disease that might otherwise have been missed due to an atypical presentation.