Tissue Dynamics and Galmed Pharmaceuticals to Develop HumanCentered Chronic Cardiac Fibrosis Platform to Advance AramcholBased Therapeutics

Image for article Tissue Dynamics and Galmed Pharmaceuticals to Develop HumanCentered Chronic Cardiac Fibrosis Platform to Advance AramcholBased Therapeutics
News Source : PRNewswire

News Summary

  • Tissue Dynamics and Galmed are collaborating on the development of the new platform as a high-throughput, human-centered model of chronic cardiac fibrosis.
  • The platform will combine Tissue Dynamics' highly physiological vascularized, multichambered cardiac organoids with embedded metabolic sensors, massive automation, and continuous real-time monitoring.
  • By monitoring thousands of organoids over time and applying AI-powered analysis, the model is expected to support rapid evaluation of Aramchol-based therapeutic approaches.
Novel vascularized, sensorembedded cardiac organoid model will focus on chronic postMI remodeling and HFpEF, linking lipid metabolism, SCD1 activity, fibrosis, and impaired tissue repairREHOVOT, [+11741 chars]

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